Journal Club with Dr. Peter Attia | Metformin for Longevity & The Power of Belief Effects

The 4-Hour Body

Tim Ferriss

“I still am a big fan of Tim ferriss's uh slow carbohydrate diet because I like to eat meat and vegetables and starches”— Andrew Huberman

Metformin (Glucophage)

Bristol-Myers Squibb (inferred)

“this is a drug that's been around forever trade name glucophage or brand name and uh but but again it's you know it's a generic drug today”— Peter Attia

Berberine

“if I took berberine and I don't recall the milligram count and then I ate you know 12 donuts I felt fine it was as if I had eaten one donut”— Andrew Huberman

Rapamycin

“rapamycin has been studied several times it's always worked another one we should talk about at a subsequent time is 17 Alpha estradiol”— Peter Attia

Acarbose

“a carbos is another one of those drugs that actually found a survival benefit in the ITP and it was a very interesting finding”— Peter Attia

Canagliflozin (SGLT2 inhibitor)

Janssen (inferred)

“canaga flows in an sglt2 inhibitor also very successful in the ITP but again interestingly rapid metformin not”— Peter Attia

Ozempic

Novo Nordisk (inferred)

“glp-1 agonists are another drug they increase insulin sensitivity initially causing you to also make more insulin um so that's ozempic yes”— Peter Attia

Adderall

“ADHD drugs so things like Adderall Vyvanse methamphetamine for that matter um Ritalin yeah why it's counter-intuitive that a stimulant would be a treatment”— Andrew Huberman

Vyvanse

“ADHD drugs so things like Adderall Vyvanse methamphetamine for that matter um Ritalin yeah why it's counter-intuitive that a stimulant would be a treatment”— Andrew Huberman

Ritalin

“ADHD drugs so things like Adderall Vyvanse methamphetamine for that matter um Ritalin yeah why it's counter-intuitive that a stimulant would be a treatment”— Andrew Huberman

Nicorette gum

Nicorette (inferred)

“which must be miserable for those people you can't have Nicorette gum or anything no nothing they must be dying”— Andrew Huberman

Zyn

Swedish Match (inferred)

“we know that nicotine Vaped smoked dipped or snuffed or these little Zin pouches or taken in capsule form does improve cognitive performance”— Andrew Huberman

Eight Sleep

Eight Sleep

“when you take a sleep supplement you can look at your eight sleep and go oh my sleep is getting better like there's a biomarker”— Peter Attia