Home Andrew Huberman Episode
Andrew Huberman · 2025-11-03

How A Doctor Cured His Own Terminal Disease | Dr. David Fajgenbaum

How A Doctor Cured His Own Terminal Disease | Dr. David Fajgenbaum

Recommended on this episode

BookRecommendedISBN verified

The Comfort Crisis

Michael Easter

“an incredible book, really... an important book”
“We had a guest on this podcast, Michael Easter. He wrote the book "The Comfort Crisis." It was an incredible book... an important book”— Andrew Huberman

Also referenced (named, not recommended)

BookReferencedISBN verified

Protocols: An Operating Manual for the Human Body

Andrew Huberman

“It's entitled "Protocols: An Operating Manual for the Human Body." This is a book that I've been working on for more than five years”— Andrew Huberman
ProductReferenced

Sirolimus (Rapamycin)

Wyeth Pharmaceuticals (inferred)

“Sirolimus had never been used before. Rapamycin's the other name for this drug... it's approved for organ transplant rejection”— David Fajgenbaum
ProductReferenced

Tocilizumab

Kazu Yoshizaki (inferred)

“It's called tocilizumab, and it was made by a doctor named Kazu Yoshizaki... it was made for Castleman's in Japan”— David Fajgenbaum
ProductReferenced

Lidocaine

generic (inferred)

“women who had localized breast cancer, if they had lidocaine injected around the tumor before surgery... there was a 29% reduction in mortality”— David Fajgenbaum
ProductReferenced

Thalidomide

generic (inferred)

“the first one's thalidomide. You probably have heard about the horrible birth defects that thalidomide caused... it's FDA-approved for leprosy”— David Fajgenbaum
ProductReferenced

Pembrolizumab

generic (inferred)

“one of my favorite examples is a drug called pembrolizumab, that is now used for dozens of cancers, but initially it was first developed for melanoma”— David Fajgenbaum
ProductReferenced

Colchicine

generic (inferred)

“colchicine is typically utilized for gout... it has a very substantial reduction in heart disease risk if you had a prior heart attack”— David Fajgenbaum
ProductReferenced

DFMO (eflornithine)

generic (inferred)

“no one should suffer from Bachmann-Bupp without being on DFMO... a drug that was made for African sleeping sickness”— David Fajgenbaum
ProductReferenced

Ruxolitinib

generic (inferred)

“we recommended her doctor try ruxolitinib, first time ever for Castleman disease, and she responded incredibly well”— David Fajgenbaum
ProductReferenced

Adalimumab (TNF inhibitor)

generic (inferred)

“we gave him adalimumab, and he responded incredibly well. He's been doing great now for two years. Published in "The New England Journal of Medicine"”— David Fajgenbaum
ProductReferenced

Viagra (sildenafil)

Pfizer (inferred)

“Many folks have probably heard about how Viagra was repurposed from heart disease to its well-known use... also been repurposed for a rare pediatric lung disease.”— David Fajgenbaum
ProductReferenced

Cialis (tadalafil)

Eli Lilly (inferred)

“isn't it that the cousin of Viagra, Cialis, was initially tadalafil, used to encourage prostate health, circulation to the prostate”— Andrew Huberman
ProductReferenced

Aspirin

generic (inferred)

“aspirin also has been shown to reduce risk of recurrence of colon cancer. Particularly, individuals with colon cancer who have a mutation”— David Fajgenbaum
ProductReferenced

Nicorette (nicotine gum)

Nicorette (inferred)

“I noticed he chewed six pieces of Nicorette inside of the 45 minutes we met... "Nicotine is protective against Alzheimer's and Parkinson's."”— Andrew Huberman
ProductReferenced

Creatine

generic (inferred)

“I've been taking creatine since my teens because I heard back then that it would help make me stronger and it'll make you stronger.”— Andrew Huberman
ProductReferenced

Mucuna pruriens

generic (inferred)

“Mucuna pruriens is this velvety bean that is 99% L-DOPA... You can buy this over the counter.”— Andrew Huberman